Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(E)-2-(4-fluorophenylsulfonyl)-3-(1-(3-nitrophenylsulfonyl)-1H-pyrrol-2-yl)acrylonitrile | compound inhibits PME-1 with more than100fold selectivity relative to other serine hydrolases in human cells. Application reduces the demethylated form of substrate protein phosphatase 2A in living cells | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0006 | - |
pH 7.5, 37°C | Homo sapiens | (E)-2-(4-fluorophenylsulfonyl)-3-(1-(3-nitrophenylsulfonyl)-1H-pyrrol-2-yl)acrylonitrile |