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Literature summary for 3.1.1.6 extracted from
- Temperature-sensitive acetylesterase activity of haemagglutinin-esterase specified by respiratory bovine coronaviruses (2000), J. Med. Microbiol., 49, 1119-1127.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| respiratory and enteropathogenic coronaviruses, DNA and amino acid sequence determination and analysis, transient and functional expression in COS-7 cells | Alphacoronavirus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| additional information | viruses are located in the cytoplasm and at perinuclear sites in the transfected COS-7 cells | Alphacoronavirus | - |
- |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Alphacoronavirus | enzyme has receptor-destroying enzyme function | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Alphacoronavirus | - |
different strains of respiratory and enteropathogenic viruses, bovine, isolated from nasal swab samples and lung tissues of feedlot cattle with acute respiratory tract disease, the viruses exhibiting distinct phenotype features from enteropathogenic bovine coronaviruses | - |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| glycoprotein | - |
Alphacoronavirus |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| purification of virus tissue material, nasal swab and from COS-7 cells | Alphacoronavirus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-nitrophenyl acetate + H2O | serine esterase activity | Alphacoronavirus | 4-nitrophenol + acetate | - |
? | |
| 9-O-acetyl sialic acid + H2O | - |
Alphacoronavirus | sialic acid + acetate | - |
? | |
| bovine submaxillary mucin + H2O | - |
Alphacoronavirus | deacetylated bovine submaxillary mucin + acetate | - |
? | |
| additional information | enzyme has receptor-destroying enzyme function | Alphacoronavirus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| AE | - |
Alphacoronavirus |
| haemagglutinin-esterase | - |
Alphacoronavirus |
| HE | - |
Alphacoronavirus |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
respiratory virus enzyme | Alphacoronavirus |
| 39 | - |
enteropathogenic virus enzyme | Alphacoronavirus |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
40 min, the transiently expressed respiratory viruses show significantly reduced activity, while the transiently expressed enteropathogenic viruses are stable | Alphacoronavirus |
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