Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli HMS174 cells | Staphylococcus aureus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Staphylococcus aureus | 16020 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
[(4-D-Ala)-(2-GlcNAc)-Rib-ol-P]n-[Gro-P]m-ManNAc-GlcNAc-PP-peptidoglycan + H2O | Staphylococcus aureus | - |
[(2-GlcNAc)-Rib-ol-P]n-[Gro-P]m-ManNAc-GlcNAc-PP-peptidoglycan + D-alanine | - |
? | |
[(4-D-Ala)-(2-GlcNAc)-Rib-ol-P]n-[Gro-P]m-ManNAc-GlcNAc-PP-peptidoglycan + H2O | Staphylococcus aureus KSA8 | - |
[(2-GlcNAc)-Rib-ol-P]n-[Gro-P]m-ManNAc-GlcNAc-PP-peptidoglycan + D-alanine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Staphylococcus aureus | O50608 | - |
- |
Staphylococcus aureus KSA8 | O50608 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Staphylococcus aureus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
[(4-D-Ala)-(2-GlcNAc)-Rib-ol-P]n-[Gro-P]m-ManNAc-GlcNAc-PP-peptidoglycan + H2O | - |
Staphylococcus aureus | [(2-GlcNAc)-Rib-ol-P]n-[Gro-P]m-ManNAc-GlcNAc-PP-peptidoglycan + D-alanine | - |
? | |
[(4-D-Ala)-(2-GlcNAc)-Rib-ol-P]n-[Gro-P]m-ManNAc-GlcNAc-PP-peptidoglycan + H2O | - |
Staphylococcus aureus KSA8 | [(2-GlcNAc)-Rib-ol-P]n-[Gro-P]m-ManNAc-GlcNAc-PP-peptidoglycan + D-alanine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
fmtA | - |
Staphylococcus aureus |
Organism | Comment | Expression |
---|---|---|
Staphylococcus aureus | the transcription of the enzyme is not changed by the addition of vancomycin or tetracycline | additional information |
Staphylococcus aureus | the transcription of the enzyme is dose dependently increased by the addition of beta-lactam antibiotics, fosfomycin, and bacitracin | up |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme affects the methicillin resistance level in methicillin-resistant Staphylococcus aureus | Staphylococcus aureus |