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Literature summary for 2.8.2.21 extracted from

  • Hiraoka, N.; Petryniak, B.; Kawashima, H.; Mitoma, J.; Akama, T.O.; Fukuda, M.N.; Lowe, J.B.; Fukuda, M.
    Significant decrease in alpha1,3-linked fucose in association with increase in 6-sulfated N-acetylglucosamine in peripheral lymph node addressin of FucT-VII-deficient mice exhibiting diminished lymphocyte homing (2007), Glycobiology, 17, 277-293.
    View publication on PubMed
Search for more literature for 2.8.2.21

Cloned(Commentary)

Cloned (Comment) Organism
expression in CHO cells Mus musculus

Protein Variants

Protein Variants Comment Organism
additional information overexpression of KSST suppresses the expression of sialyl Lewis X on CHO cells engineered to express sialyl Lewis X, KSST expression in those cells suppresses lymphocyte rolling compared with mock-transfected CHO cells expressing 6-sulfo sialyl Lewis X, overview Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3'-phosphoadenylyl sulfate + keratan Mus musculus
-
 adenosine 3',5'-bisphosphate + keratan 6'-sulfate
-
 ?
3'-phosphoadenylyl sulfate + N-acetyllactosamine Mus musculus
-
 adenosine 3',5'-bisphosphate + 6'-sulfo N-acetyllactosamine
-
 ?
additional information Mus musculus KSST competes with fucosyltransferase-VII for the same acceptor substrate and downregulates the synthesis of L-selectin ligand by inhibiting alpha1,3-fucosylation, sulfated oligosaccharide, e.g. 6'-sulfated galactose residues, increase in FucT-VII-deficient mutant mice, structure of mono-sulfated O-glycans, detailed overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
lymph node peripheral Mus musculus
-
lymphocyte
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylyl sulfate + keratan
-
 Mus musculus adenosine 3',5'-bisphosphate + keratan 6'-sulfate
-
 ?
3'-phosphoadenylyl sulfate + N-acetyllactosamine
-
 Mus musculus adenosine 3',5'-bisphosphate + 6'-sulfo N-acetyllactosamine
-
 ?
additional information KSST competes with fucosyltransferase-VII for the same acceptor substrate and downregulates the synthesis of L-selectin ligand by inhibiting alpha1,3-fucosylation, sulfated oligosaccharide, e.g. 6'-sulfated galactose residues, increase in FucT-VII-deficient mutant mice, structure of mono-sulfated O-glycans, detailed overview Mus musculus ?
-
 ?

Synonyms

Synonyms Comment Organism
keratan sulfate sulfotransferase
-
 Mus musculus
KSST
-
 Mus musculus