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Literature summary for 2.7.8.2 extracted from

  • Zayed, M.A.; Jin, X.; Yang, C.; Belaygorod, L.; Engel, C.; Desai, K.; Harroun, N.; Saffaf, O.; Patterson, B.W.; Hsu, F.F.; Semenkovich, C.F.
    CEPT1-mediated phospholipogenesis regulates endothelial cell function and ischemia-induced angiogenesis through PPARalpha (2020), Diabetes, 70, 549-561 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.8.2

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9Y6K0 cf. EC 2.7.8.1
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Mus musculus Q8BGS7 cf. EC 2.7.8.1
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Source Tissue

Source Tissue Comment Organism Textmining
artery CEPT1 is elevated in diseased lower extremity arterial intima of individuals with peripheral arterial disease and diabetes Homo sapiens
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artery CEPT1 is elevated in diseased lower extremity arterial intima of individuals with peripheral arterial disease and diabetes Mus musculus
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carotid artery CEPT1 is elevated in carotid plaque of patients with diabetes Homo sapiens
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carotid artery CEPT1 is elevated in carotid plaque of patients with diabetes Mus musculus
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endothelium CEPT1 is elevated in diseased lower extremity arterial intima of individuals with peripheral arterial disease and diabetes Homo sapiens
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endothelium CEPT1 is elevated in diseased lower extremity arterial intima of individuals with peripheral arterial disease and diabetes Mus musculus
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Synonyms

Synonyms Comment Organism
CEPT1 cf. EC 2.7.8.1 Homo sapiens
CEPT1 cf. EC 2.7.8.1 Mus musculus
choline/ethanolaminephosphotransferase 1
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 Mus musculus

General Information

General Information Comment Organism
physiological function endothelial cells of mice carrying a conditional endothelial cell-specific deletion of Cept1 demonstrate decreased proliferation, migration, and tubule formation, and mice carrying the conditional deletion have reduced perfusion and angiogenesis in ischemic hind-limbs. Peripheral ischemic recovery and PPARalpha signaling is further compromised by Streptozotocin-induced diabetes, and ameliorated by feeding fenofibrate Mus musculus