Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9Y6K0 | cf. EC 2.7.8.2 | - |
Mus musculus | Q8BGS7 | cf. EC 2.7.8.2 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
artery | CEPT1 is elevated in diseased lower extremity arterial intima of individuals with peripheral arterial disease and diabetes | Homo sapiens | - |
artery | CEPT1 is elevated in diseased lower extremity arterial intima of individuals with peripheral arterial disease and diabetes | Mus musculus | - |
carotid artery | CEPT1 is elevated in carotid plaque of patients with diabetes | Homo sapiens | - |
carotid artery | CEPT1 is elevated in carotid plaque of patients with diabetes | Mus musculus | - |
endothelium | CEPT1 is elevated in diseased lower extremity arterial intima of individuals with peripheral arterial disease and diabetes | Homo sapiens | - |
endothelium | CEPT1 is elevated in diseased lower extremity arterial intima of individuals with peripheral arterial disease and diabetes | Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
CEPT1 | cf. EC 2.7.8.2 | Homo sapiens |
CEPT1 | cf. EC 2.7.8.2 | Mus musculus |
choline/ethanolaminephosphotransferase 1 | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
physiological function | endothelial cells of mice carrying a conditional endothelial cell-specific deletion of Cept1 demonstrate decreased proliferation, migration, and tubule formation, and mice carrying the conditional deletion have reduced perfusion and angiogenesis in ischemic hind-limbs. Peripheral ischemic recovery and PPARalpha signaling is further compromised by Streptozotocin-induced diabetes, and ameliorated by feeding fenofibrate | Mus musculus |