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Literature summary for 2.7.4.16 extracted from

  • Sullivan, A.H.; Dranow, D.M.; Horanyi, P.S.; Lorimer, D.D.; Edwards, T.E.; Abendroth, J.
    Crystal structures of thiamine monophosphate kinase from Acinetobacter baumannii in complex with substrates and products (2019), Sci. Rep., 9, 4392 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Rosetta BL21(DE3)R3 Acinetobacter baumannii

Crystallization (Commentary)

Crystallization (Comment) Organism
sitting drop method, crystal structures of thiamine monophosphate kinase in complex with a pair of substrates TMP and a non-hydrolyzable adenosine triphosphate analog, and in complex with a pair of products TPP and adenosine diphosphate Acinetobacter baumannii

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + thiamine phosphate Acinetobacter baumannii
-
ADP + thiamine diphosphate
-
?
ATP + thiamine phosphate Acinetobacter baumannii AB5075-UW
-
ADP + thiamine diphosphate
-
?

Organism

Organism UniProt Comment Textmining
Acinetobacter baumannii A0A0D5YC82
-
-
Acinetobacter baumannii AB5075-UW A0A0D5YC82
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Acinetobacter baumannii

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + thiamine phosphate
-
Acinetobacter baumannii ADP + thiamine diphosphate
-
?
ATP + thiamine phosphate
-
Acinetobacter baumannii AB5075-UW ADP + thiamine diphosphate
-
?

Synonyms

Synonyms Comment Organism
thiamine monophosphate kinase
-
Acinetobacter baumannii