Literature summary for 2.7.13.3 extracted from

Hashiguchi, Y.; Tezuka, T.; Mouri, Y.; Konishi, K.; Fujita, A.; Hirata, A.; Ohnishi, Y.
Regulation of sporangium formation, spore dormancy, and sporangium dehiscence by a hybrid sensor histidine kinase in Actinoplanes missouriensis Relationship with the global transcriptional regulator TcrA (2020), J. Bacteriol., 202, e00228 .

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Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
additional information	no signal peptide or transmembrane region is predicted	Actinoplanes missouriensis	-	-

Organism

Organism	UniProt	Comment	Textmining
Actinoplanes missouriensis	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

Synonyms

Synonyms	Comment	Organism
HhkA	-	Actinoplanes missouriensis
orphan hybrid histidine kinase	-	Actinoplanes missouriensis

Expression

Organism	Comment	Expression
Actinoplanes missouriensis	HhkA is actively transcribed during sporangium formation and dehiscence	additional information

General Information

General Information	Comment	Organism
physiological function	sporangia of an HhkA deletion mutant contain many distorted or ectopically germinated spores and scarcely open to release the spores under sporangium dehiscence-inducing conditions. HhkA regulates a signal transduction pathway involved in sporangium formation, spore dormancy, and sporangium dehiscence. Genes regulated by HhkA overlap mostly with global transcriptional activator TcrA-regulated genes. The interaction between HhkA and TcrA is very weak and probably transient	Actinoplanes missouriensis

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Release 2023.1 (January 2023)