Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | - |
Rattus norvegicus | 5737 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
90000 | - |
SDS-PAGE | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + dynamin 1 | Rattus norvegicus | - |
ADP + phosphorylated dynamin 1 | - |
? | |
additional information | Rattus norvegicus | neither clathrin heavy chain nor endophilin 1 is phosphorylated by the Dyrk1A | ? | - |
? |
Organic Solvent | Comment | Organism |
---|---|---|
Triton X-100 | the kinase is resistant to high salt and Triton X-100 extraction at pH 6.5. At pH 7.4, the kinase becomes soluble to some extent after treatment with Triton X-100 and 1.0 M NaCl | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
hydroxylapatite column chromatography | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Rattus norvegicus | - |
neuron | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + dynamin 1 | - |
Rattus norvegicus | ADP + phosphorylated dynamin 1 | - |
? | |
additional information | neither clathrin heavy chain nor endophilin 1 is phosphorylated by the Dyrk1A | Rattus norvegicus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
dual-specificity tyrosine phosphorylation-regulated kinase | - |
Rattus norvegicus |
DYRK1A | - |
Rattus norvegicus |
pH Stability | pH Stability Maximum | Comment | Organism |
---|---|---|---|
6.5 | 7.4 | the kinase is resistant to high salt and Triton X-100 extraction at pH 6.5. At pH 7.4, the kinase becomes soluble to some extent after treatment with Triton X-100 and 1.0 M NaCl | Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Rattus norvegicus |