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Literature summary for 2.7.11.28 extracted from

  • Montgomery, K.; Mak, A.S.
    In vitro phosphorylation of tropomyosin by a kinase from chicken embryo (1984), J. Biol. Chem., 259, 5555-5560.
    View publication on PubMed
Search for more literature for 2.7.11.28

Inhibitors

Inhibitors Comment Organism Structure
Ca2+ 3 mM Gallus gallus
KCl high concentrations Gallus gallus

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ requirement Gallus gallus
additional information no activation by Ca2+ Gallus gallus

Organism

Organism UniProt Comment Textmining
Gallus gallus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Gallus gallus

Source Tissue

Source Tissue Comment Organism Textmining
embryo
-
 Gallus gallus
-
muscle thigh and leg Gallus gallus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.0004
-
-
 Gallus gallus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + tropomyosin other poor substrates are beta-tropomyosin from chicken leg muscle, rabbit skeletal muscle Gallus gallus ADP + O-phosphotropomyosin
-
 ?
ATP + tropomyosin the phosphorylation site is a single serine-residue close to COOH-terminus, i.e Ser-283 Gallus gallus ADP + O-phosphotropomyosin
-
 ?
ATP + tropomyosin alpha-tropomyosin subunit preferred over beta-tropomyosin subunit Gallus gallus ADP + O-phosphotropomyosin
-
 ?
additional information no substrates are smooth muscle myosin light chain from turkey gizzard, tropomyosin from platelet and erythrocyte from chicken gizzard and smooth muscle Gallus gallus ?
-
 ?
additional information no substrates are gamma- or beta-tropomyosin from smooth muscle from chicken gizzard Gallus gallus ?
-
 ?

Cofactor

Cofactor Comment Organism Structure
additional information no activation by cAMP or calmodulin Gallus gallus