Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.11.26 extracted from

  • Boom, A.; Authelet, M.; Dedecker, R.; Frederick, C.; Van Heurck, R.; Daubie, V.; Leroy, K.; Pochet, R.; Brion, J.P.
    Bimodal modulation of tau protein phosphorylation and conformation by extracellular Zn2+ in human-tau transfected cells (2009), Biochim. Biophys. Acta, 1793, 1058-1067.
    View publication on PubMed
Search for more literature for 2.7.11.26

Inhibitors

Inhibitors Comment Organism Structure
SB-216763 specific inhibitor of GSK-3beta Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ high zinc concentrations (0.1-0.5 mM) increase glycogen synthase kinase-3beta phosphorylation on tyrosine 216, a phosphorylation associated with increased activity of this tau kinase, whereas the phosphorylation of GSK-3alpha at Y279 and the level of total GSK-3beta are not affected Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
47000
-
 SDS-PAGE Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
1C9 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + protein tau
-
 Homo sapiens ADP + protein tau phosphate
-
 ?

Synonyms

Synonyms Comment Organism
glycogen synthase kinase-3beta isoform Homo sapiens
GSK-3beta isoform Homo sapiens

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Homo sapiens