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Literature summary for 2.7.11.21 extracted from

  • Park, C.J.; Park, J.E.; Karpova, T.S.; Soung, N.K.; Yu, L.R.; Song, S.; Lee, K.H.; Xia, X.; Kang, E.; Dabanoglu, I.; Oh, D.Y.; Zhang, J.Y.; Kang, Y.H.; Wincovitch, S.; Huffaker, T.C.; Veenstra, T.D.; McNally, J.G.; Lee, K.S.
    Requirement for the budding yeast polo kinase Cdc5 in proper microtubule growth and dynamics (2008), Eukaryot. Cell, 7, 444-453.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
the plasmids pRS316, YEp351 and YCplac111 are used Saccharomyces cerevisiae

Protein Variants

Protein Variants Comment Organism
W565R single point mutation within the PB1 motif of the highly conserved polo box domain, mutant exhibits a temperature-sensitive growth defect Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining
kinetochore
-
Saccharomyces cerevisiae 776
-
spindle
-
Saccharomyces cerevisiae 5819
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + protein Saccharomyces cerevisiae
-
ADP + phosphoprotein
-
?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae P32562
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + Nud1 Cdc5 and Cdc28 activities are required for proper phosphorylation of Nud1 Saccharomyces cerevisiae ADP + phosphorylated Nud1
-
?
ATP + protein
-
Saccharomyces cerevisiae ADP + phosphoprotein
-
?
ATP + Slk19 Cdc5 and Cdc28 activities are required for proper phosphorylation of Slk19 Saccharomyces cerevisiae ADP + phosphorylated Slk19
-
?
ATP + Stu2 Cdc5 and Cdc28 activities are required for proper phosphorylation of Stu2 Saccharomyces cerevisiae ADP + phosphorylated Stu2
-
?

Synonyms

Synonyms Comment Organism
Cdc5
-
Saccharomyces cerevisiae

Cofactor

Cofactor Comment Organism Structure
ATP
-
Saccharomyces cerevisiae