Literature summary for 2.7.11.21 extracted from

Sato, F.; Abraham, J.M.; Yin, J.; Kan, T.; Ito, T.; Mori, Y.; Hamilton, J.P.; Jin, Z.; Cheng, Y.; Paun, B.; Berki, A.T.; Wang, S.; Shimada, Y.; Meltzer, S.J.
Polo-like kinase and survivin are esophageal tumor-specific promoters (2006), Biochem. Biophys. Res. Commun., 342, 465-471.

Search for more literature for 2.7.11.21

Application

Application	Comment	Organism
drug development	promoter of PLK is an esophageal tumor-specific promoter and may serve as useful tool in the establishment of a transcriptional targeting strategy for esophageal cancer gene therapy	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
BIC-1 cell	-	Homo sapiens	-
brain	-	Homo sapiens	-
esophageal cancer cell	is highly expressed, on average 2.7-fold higher mRNA expression levels than in normal organs excluding testis, promoter activity 18.9 higher than in normal lung and renal cells	Homo sapiens	-
FLO-1 cell	-	Homo sapiens	-
heart	-	Homo sapiens	-
kidney	-	Homo sapiens	-
liver	-	Homo sapiens	-
lung	-	Homo sapiens	-
NHBE cell	-	Homo sapiens	-
OE-33 cell	-	Homo sapiens	-
renal epithelium cell line	-	Homo sapiens	-
SEG-1 cell	-	Homo sapiens	-
testis	is highly expressed	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
PLK	-	Homo sapiens
Polo-like kinase 1	-	Homo sapiens

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Release 2023.1 (January 2023)