Literature summary for 2.7.11.13 extracted from

Ninsontia, C.; Phiboonchaiyanan, P.P.; Kiratipaiboon, C.; Chanvorachote, P.
Zinc suppresses stem cell properties of lung cancer cells through protein kinase C-mediated beta-catenin degradation (2017), Am. J. Physiol. Cell Physiol., 312, C487-C499 .

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Activating Compound

Activating Compound	Comment	Organism	Structure
A23187	-	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
bisindolylmaleimide I	highly selective PKCalpha inhibitor	Homo sapiens

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Zn2+	activates	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + beta-catenin	Homo sapiens	-	ADP + phosphorylated beta-catenin	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P17252	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
lung cancer cell	-	Homo sapiens	-
NCI-H23 cell	-	Homo sapiens	-
NCI-H292 cell	-	Homo sapiens	-
NCI-H460 cell	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + beta-catenin	-	Homo sapiens	ADP + phosphorylated beta-catenin	-	?

Subunits

Subunits	Comment	Organism
?	x * 80000, SDS-PAGE	Homo sapiens

Synonyms

Synonyms	Comment	Organism
PKCalpha	-	Homo sapiens
protein kinase C-alpha	-	Homo sapiens

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Release 2023.1 (January 2023)