Activating Compound | Comment | Organism | Structure |
---|---|---|---|
8-bromo-cGMP | - |
Rattus norvegicus | |
cGMP | level is increased by NO and glutamate | Rattus norvegicus | |
additional information | glutamate induced NO, and increased NO release from sodium nitroprusside and S-nitroso-N-acetylpenicillamine increase cGMP level which increases PKG activity, overview | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
KT5823 | specific for PKG | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + Na+/K+ ATPase | Rattus norvegicus | the enzyme has a positive regulatory function on the ion pump activity induced by No and glutamate via increased cGMP, overview | ADP + phosphorylated Na+/K+ ATPase | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
male Wistar rats | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
corpus striatum | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + Na+/K+ ATPase | - |
Rattus norvegicus | ADP + phosphorylated Na+/K+ ATPase | - |
? | |
ATP + Na+/K+ ATPase | the enzyme has a positive regulatory function on the ion pump activity induced by No and glutamate via increased cGMP, overview | Rattus norvegicus | ADP + phosphorylated Na+/K+ ATPase | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PKG | - |
Rattus norvegicus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
34 | - |
assay at, in vivo | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
assay at, in vivo | Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Rattus norvegicus |