Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | requires a co-receptor, GFRalpha, for ligand recognition and activation | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + a [protein]-L-tyrosine | Homo sapiens | - |
ADP + a [protein]-L-tyrosine phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
neuron | the enzyme is expressed primarily in peripheral enteric, sympathetic and sensory neurons, and in central motor, dopamine and noradrenaline neurons | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + a [protein]-L-tyrosine | - |
Homo sapiens | ADP + a [protein]-L-tyrosine phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CLD1 | - |
Homo sapiens |
CLD2 | - |
Homo sapiens |
receptor tyrosine kinase | - |
Homo sapiens |
RET | - |
Homo sapiens |
RTK | - |
Homo sapiens |