Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | the activation of PKCdelta is strongly related to the glycosaminoglycans, especially chondroitin sulfate on the plasma membrane | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
rottlerin | specific inhibitor of PKCdelta | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
nucleus | - |
Mus musculus | 5634 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
80000 | - |
full-length enzyme, SDS-PAGE | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + a [protein]-L-tyrosine | Mus musculus | - |
ADP + a [protein]-L-tyrosine phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | PKCd eltais activated by phosphorylation of a tyrosine residue in the catalytic domain and a threonine residue in the regulatory domain | Mus musculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
RAW-264.7 cell | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + a [protein]-L-tyrosine | - |
Mus musculus | ADP + a [protein]-L-tyrosine phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PKCdelta | - |
Mus musculus |
protein kinase Cdelta | - |
Mus musculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
physiological function | PKCeltad is strongly associated with apoptosis induced by stearylamine-liposomes | Mus musculus |