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Literature summary for 2.7.1.32 extracted from
- Deletion and alanine mutation analyses for the formation of active homo- or hetero-dimer complexes of mouse choline kinase-alpha and -beta (2006), Biochim. Biophys. Acta, 1761, 111-120.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in COS-7 cells | Mus musculus |
| expression in COS-7 cells | Mus musculus |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.032 | - |
choline | isozyme CK-beta | Mus musculus |  |
| 0.055 | - |
choline | isozyme CK-alpha1/beta | Mus musculus | |
| 0.083 | - |
choline | isozyme CK-alpha | Mus musculus | |
| 0.157 | - |
choline | N-terminal truncated enzyme version of CK-beta | Mus musculus | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | required for activity | Mus musculus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + choline | - |
Mus musculus | ADP + O-phosphocholine | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | 60% of the active enzyme exists as homodimer and 20% as heterodimer | Mus musculus |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CK-alpha | - |
Mus musculus |
| CK-alpha1/beta | - |
Mus musculus |
| CK-beta | - |
Mus musculus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Mus musculus | |
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