Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Formycin A | IC50 is 0.00027 mM, inhibits growth of Trichomonas vaginalis, addition of adenine prevents growth inhibition, but not the addition of guanine and hypoxanthine | Trichomonas vaginalis |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | - |
Trichomonas vaginalis | 5737 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
diphosphate + adenosine | Trichomonas vaginalis | - |
phosphate + AMP | - |
? | |
diphosphate + adenosine | Trichomonas vaginalis 3001 | - |
phosphate + AMP | - |
? | |
diphosphate + guanosine | Trichomonas vaginalis | - |
phosphate + GMP | - |
? | |
diphosphate + guanosine | Trichomonas vaginalis 3001 | - |
phosphate + GMP | - |
? | |
diphosphate + inosine | Trichomonas vaginalis | - |
phosphate + IMP | - |
? | |
additional information | Trichomonas vaginalis | adenine is the precursor of the entire purine nucleotide pool in Trichomonas vaginalis, the enzyme is involved in replenishing of the purine pool in the organism, probable purine salvage pathway, overview | ? | - |
? | |
additional information | Trichomonas vaginalis 3001 | adenine is the precursor of the entire purine nucleotide pool in Trichomonas vaginalis, the enzyme is involved in replenishing of the purine pool in the organism, probable purine salvage pathway, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Trichomonas vaginalis | - |
- |
- |
Trichomonas vaginalis 3001 | - |
- |
- |
Purification (Comment) | Organism |
---|---|
partially by ATP affinity chromatography | Trichomonas vaginalis |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
additional information | the organism can grow on adenine, but not on guanine or hypoxanthine added to the culture medium | Trichomonas vaginalis | - |
trophozoite | - |
Trichomonas vaginalis | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
diphosphate + adenosine | - |
Trichomonas vaginalis | phosphate + AMP | - |
? | |
diphosphate + adenosine | - |
Trichomonas vaginalis 3001 | phosphate + AMP | - |
? | |
diphosphate + guanosine | - |
Trichomonas vaginalis | phosphate + GMP | - |
? | |
diphosphate + guanosine | - |
Trichomonas vaginalis 3001 | phosphate + GMP | - |
? | |
diphosphate + inosine | - |
Trichomonas vaginalis | phosphate + IMP | - |
? | |
additional information | adenine is the precursor of the entire purine nucleotide pool in Trichomonas vaginalis, the enzyme is involved in replenishing of the purine pool in the organism, probable purine salvage pathway, overview | Trichomonas vaginalis | ? | - |
? | |
additional information | adenine is the precursor of the entire purine nucleotide pool in Trichomonas vaginalis, the enzyme is involved in replenishing of the purine pool in the organism, probable purine salvage pathway, overview | Trichomonas vaginalis 3001 | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PNK | - |
Trichomonas vaginalis |
purine nucleoside kinase | - |
Trichomonas vaginalis |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Trichomonas vaginalis |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.2 | - |
assay at | Trichomonas vaginalis |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00027 | - |
IC50 is 0.00027 mM, inhibits growth of Trichomonas vaginalis, addition of adenine prevents growth inhibition, but not the addition of guanine and hypoxanthine | Trichomonas vaginalis | Formycin A |