Literature summary for 2.7.1.11 extracted from

Liu, S.; Kang, P.; Cui, Z.; Wang, Z.; Chen, T.
Increased riboflavin production by knockout of 6-phosphofructokinase I and blocking the Entner-Doudoroff pathway in Escherichia coli (2016), Biotechnol. Lett., 38, 1307-1314 .

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Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	P0A796	-	-
Escherichia coli K12	P0A796	-	-

Synonyms

Synonyms	Comment	Organism
6-phosphofructokinase I	-	Escherichia coli
PFKA	-	Escherichia coli

General Information

General Information	Comment	Organism
malfunction	a knockout of 6-phosphofructokinase I and blocking of the Entner-Doudoroff pathway efficiently increased riboflavin production in Escherichia coli	Escherichia coli
metabolism	in Escherichia coli, the phosphorylation of fructose-6-phosphate is catalyzed by two isozymes, 6-phosphofructokinase I (pfkA) and 6-phosphofructokinase II (pfkB). More than 90% of the phosphofructokinase activity relies on pfkA. A knockout of 6-phosphofructokinase I and blocking of the Entner-Doudoroff pathway efficiently increased riboflavin production in Escherichia coli	Escherichia coli

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Release 2023.1 (January 2023)