Activating Compound | Comment | Organism | Structure |
---|---|---|---|
L-arginine | induces the L-ATase activity at least 76fold in an aruF mutant strain, but not in the wild-type strain PAO1 | Pseudomonas aeruginosa |
Cloned (Comment) | Organism |
---|---|
gene aruH or PA4976, location in the aruIH locus | Pseudomonas aeruginosa |
Protein Variants | Comment | Organism |
---|---|---|
additional information | construction of the PA4976 aruH knockout mutant | Pseudomonas aeruginosa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Pseudomonas aeruginosa | arginine utilization proceeds via multiple catabolic pathways in the organism, the enzyme is involved in the arginine transaminase pathway, regulation of arginine-responsive induction of the arginine transaminase pathway, arginine metabolism, overview | ? | - |
? | |
additional information | Pseudomonas aeruginosa | knockout of aruH and aruI, which encode an arginine:pyruvate transaminase and a 2-ketoarginine decarboxylase in an operon, also abolishes the ability of the aruF mutant to grow on L-arginine | ? | - |
? | |
additional information | Pseudomonas aeruginosa PAO4558 | arginine utilization proceeds via multiple catabolic pathways in the organism, the enzyme is involved in the arginine transaminase pathway, regulation of arginine-responsive induction of the arginine transaminase pathway, arginine metabolism, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pseudomonas aeruginosa | - |
- |
- |
Pseudomonas aeruginosa | - |
and several strains derived thereof, gene aruH | - |
Pseudomonas aeruginosa | Q9HUI9 | - |
- |
Pseudomonas aeruginosa PAO4558 | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
L-arginine + pyruvate = 5-guanidino-2-oxopentanoate + L-alanine | aruF mutant with inducible L-arginine:pyruvate transaminase activity | Pseudomonas aeruginosa |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Pseudomonas aeruginosa |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-arginine + pyruvate | - |
Pseudomonas aeruginosa | 5-guanidino-2-oxopentanoate + L-alanine | - |
? | |
L-arginine + pyruvate | - |
Pseudomonas aeruginosa PAO4558 | 5-guanidino-2-oxopentanoate + L-alanine | - |
? | |
additional information | arginine utilization proceeds via multiple catabolic pathways in the organism, the enzyme is involved in the arginine transaminase pathway, regulation of arginine-responsive induction of the arginine transaminase pathway, arginine metabolism, overview | Pseudomonas aeruginosa | ? | - |
? | |
additional information | AruH is also an L-ATase, overview | Pseudomonas aeruginosa | ? | - |
? | |
additional information | knockout of aruH and aruI, which encode an arginine:pyruvate transaminase and a 2-ketoarginine decarboxylase in an operon, also abolishes the ability of the aruF mutant to grow on L-arginine | Pseudomonas aeruginosa | ? | - |
? | |
additional information | arginine utilization proceeds via multiple catabolic pathways in the organism, the enzyme is involved in the arginine transaminase pathway, regulation of arginine-responsive induction of the arginine transaminase pathway, arginine metabolism, overview | Pseudomonas aeruginosa PAO4558 | ? | - |
? | |
additional information | AruH is also an L-ATase, overview | Pseudomonas aeruginosa PAO4558 | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
arginine:pyruvate transaminase | - |
Pseudomonas aeruginosa |
aruF mutant | - |
Pseudomonas aeruginosa |
AruH | - |
Pseudomonas aeruginosa |
ATASE | detected, when pyruvate is used as the amino group acceptor | Pseudomonas aeruginosa |
L-arginine inducible arginine:pyruvate transaminase | - |
Pseudomonas aeruginosa |