Literature summary for 2.6.1.76 extracted from

Ikai, H.; Yamamoto, S.
Two genes involved in the 1,3-diaminopropane production pathway in Haemophilus influenzae (1998), Biol. Pharm. Bull., 21, 170-173.

Search for more literature for 2.6.1.76

Application

Application	Comment	Organism
medicine	-	Acinetobacter baumannii
medicine	responsible for many human infections including otitis media, meningitis, epiglottis and pneumonia	Haemophilus influenzae

Cloned(Commentary)

Cloned (Comment)	Organism
Escherichia coli clone carrying the dat homolog of H. influenzae	Haemophilus influenzae

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
49400	-	predicted from amino acid sequence, gene HI0949	Haemophilus influenzae
56200	-	predicted from amino acid sequence, gene HI946	Haemophilus influenzae

Organism

Organism	UniProt	Comment	Textmining
Acinetobacter baumannii	-	-	-
Haemophilus influenzae	-	Rd, types a, b, d, e, f	-

Reaction

Reaction	Comment	Organism	Reaction ID
L-2,4-diaminobutanoate + 2-oxoglutarate = L-aspartate 4-semialdehyde + L-glutamate	Involved in the formation of 1,3-diaminopropane in Haemophilus influenzae and Acinetobacter baumannii. A product of the ddc gene that also encodes L-2,4-diaminobutyrate decarboxylase in Acinetobacter baumannii. Differs from EC 2.6.1.46 diaminobutyrate-pyruvate transaminase, which has pyruvate as the amino-group acceptor	Acinetobacter baumannii	a

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-2,4-diaminobutyric acid + 2-oxoglutaric acid	-	Haemophilus influenzae	L-glutamic acid + L-aspartic beta-semialdehyde	-	?
L-2,4-diaminobutyric acid + 2-oxoglutaric acid	-	Acinetobacter baumannii	L-glutamic acid + L-aspartic beta-semialdehyde	-	r
L-glutamic acid + L-aspartic beta-semialdehyde	-	Haemophilus influenzae	L-2,4-diaminobutyric acid + 2-oxoglutaric acid	-	?
L-glutamic acid + L-aspartic beta-semialdehyde	-	Acinetobacter baumannii	L-2,4-diaminobutyric acid + 2-oxoglutaric acid	-	r

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Release 2023.1 (January 2023)