Literature summary for 2.6.1.7 extracted from

Wyckelsma, V.L.; Lindkvist, W.; Venckunas, T.; Brazaitis, M.; Kamandulis, S.; Paeaesuke, M.; Ereline, J.; Westerblad, H.; Andersson, D.C.
Kynurenine aminotransferase isoforms display fiber-type specific expression in young and old human skeletal muscle (2020), Exp. Gerontol., 134, 110880 .

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Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
mitochondrion	-	Homo sapiens	5739	-

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
L-kynurenine + 2-oxoglutarate	Homo sapiens	-	4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate + H2O	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-
Homo sapiens	Q6YP21	-	-
Homo sapiens	Q8N5Z0	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
skeletal muscle	the enzyme is generally more expressed in oxidative muscle fibers	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-kynurenine + 2-oxoglutarate	-	Homo sapiens	4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate + H2O	-	?

Synonyms

Synonyms	Comment	Organism
KAT I	isoform	Homo sapiens
KAT III	isoform	Homo sapiens
KAT IV	isoform	Homo sapiens
kynurenine aminotransferase	-	Homo sapiens

Cofactor

Cofactor	Comment	Organism	Structure
pyridoxal 5'-phosphate	-	Homo sapiens

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Release 2023.1 (January 2023)