Any feedback?
Literature summary for 2.6.1.45 extracted from
- Serine-glyoxylate aminotransferase from kidney bean (Phaseolus vulgaris). II. The reverse reactions (1974), Biochim. Biophys. Acta, 370, 96-101.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| hydroxylamine | 0.01 mM, 85% inhibition of glycin-hydroxypyruvate transamination | Phaseolus vulgaris |  |
| N-ethylmaleimide | - |
Phaseolus vulgaris | |
| NH4Cl | glycine-hydroxypyruvate transamination is only weakly inhibited | Phaseolus vulgaris | |
| p-hydroxymercuribenzoate | - |
Phaseolus vulgaris | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.63 | - |
3-hydroxypyruvate | pH 8.0, 30°C, cosubstrate L-alanine | Phaseolus vulgaris | |
| 1.1 | - |
3-hydroxypyruvate | pH 8.0, 30°C, cosubstrate glycine | Phaseolus vulgaris | |
| 11 | - |
glycine | pH 8.0, 30°C | Phaseolus vulgaris | |
| 20 | - |
L-alanine | pH 8.0, 30°C | Phaseolus vulgaris | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-serine + glyoxylate | Phaseolus vulgaris | involved in glycine metabolism | 3-hydroxypyruvate + glycine | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Phaseolus vulgaris | - |
kidney bean, cv. Red Kidney | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Phaseolus vulgaris |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| leaf | - |
Phaseolus vulgaris | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-serine + glyoxylate | reverse reaction at 4-11% the rate of forward reaction | Phaseolus vulgaris | 3-hydroxypyruvate + glycine | - |
r | |
| L-serine + glyoxylate | preferred substrates | Phaseolus vulgaris | 3-hydroxypyruvate + glycine | - |
r | |
| L-serine + glyoxylate | involved in glycine metabolism | Phaseolus vulgaris | 3-hydroxypyruvate + glycine | - |
? | |
| L-serine + pyruvate | 6% of glyoxylate transamination activity | Phaseolus vulgaris | 3-hydroxypyruvate + L-alanine | - |
r | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 30 | - |
assay at | Phaseolus vulgaris |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8.5 | - |
substrates L-alanine and 3-hydroxypyruvate | Phaseolus vulgaris |
| 9 | - |
substrates glycine and 3-hydroxypyruvate | Phaseolus vulgaris |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2026.1 (March 2026)
Legal
Curated at
Member of
![DSMZ Digital Diversity]()
![Global Core Biodata Resource]()
![ELIXIR Core Data Resource]()
![German Network for Bioinformatics Infrastructure]()
