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Literature summary for 2.5.1.150 extracted from
- lbtA and lbtB are required for production of the Legionella pneumophila siderophore legiobactin (2006), J. Bacteriol., 188, 1351-1363 .
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Legionella pneumophila | Q45RG2 | - |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| lbtA | - |
Legionella pneumophila |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Legionella pneumophila | iron repressed enzyme | down |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | mutants lacking lbtA or lbtB are defective for legiobactin, producing 40 to 70% less chrome azurol S reactivity in deferrated chemically defined medium. The lbtA mutant is modestly defective for growth in deferrated chemically defined medium containing the iron chelator citrate, indicating that legiobactin is required in conditions of severe iron limitation. The lbtA mutant replicates as the wild type does in macrophages, amoebae, and the lungs of mice | Legionella pneumophila |
| metabolism | lbtA is required for production of the Legionella pneumophila siderophore legiobactin | Legionella pneumophila |
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