Insights into diphthamide, key diphtheria toxin effector
Abdel-Fattah, W.; Scheidt, V.; Uthman, S.; Stark, M.J.; Schaffrath, R.; Toxins 5, 958-968 (2013) 
Data extracted from this reference:
Cloned(Commentary)
Cloned (Commentary)
Organism
expression in Escherrichia coli
Saccharomyces cerevisiae
Organism
Organism
UniProt
Commentary
Textmining
Saccharomyces cerevisiae
-
-
-
Synonyms
Synonyms
Commentary
Organism
Dph2
-
Saccharomyces cerevisiae
Cloned(Commentary) (protein specific)
Commentary
Organism
expression in Escherrichia coli
Saccharomyces cerevisiae
General Information
General Information
Commentary
Organism
physiological function
diphthamide biosynthesis proteins Dph1 and Dph2 interact and the first step of diphthamide formation on eukaryotic translation elongation factor eEF2 requires a complex formed in vivo between Dph1, Dph2 and Dph3
Saccharomyces cerevisiae
General Information (protein specific)
General Information
Commentary
Organism
physiological function
diphthamide biosynthesis proteins Dph1 and Dph2 interact and the first step of diphthamide formation on eukaryotic translation elongation factor eEF2 requires a complex formed in vivo between Dph1, Dph2 and Dph3
Saccharomyces cerevisiae
Other publictions for EC 2.5.1.108
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
758825
Fenwick
The crystal structure of Dph2 ...
Methanobrevibacter smithii, Methanobrevibacter smithii DSM 861
Biochemistry
58
4343-4351
2019
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759511
Dong
The asymmetric function of Dp ...
Saccharomyces cerevisiae
J. Biol. Inorg. Chem.
24
777-782
2019
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4
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1
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5
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1
1
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759725
Dong
Methods for studying the radi ...
Saccharomyces cerevisiae, Pyrococcus horikoshii, Saccharomyces cerevisiae BY4741
Methods Enzymol.
606
421-438
2018
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2
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72
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3
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2
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3
2
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759402
Dong
Substrate-dependent cleavage ...
Pyrococcus horikoshii
J. Am. Chem. Soc.
139
5680-5683
2017
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1
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1
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1
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738461
Dong
An organometallic complex form ...
Pyrococcus horikoshii
J. Am. Chem. Soc.
138
9755-9758
2016
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739730
Abdel-Fattah
Insights into diphthamide, key ...
Saccharomyces cerevisiae
Toxins
5
958-968
2013
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723158
Zhu
Mechanistic understanding of P ...
Pyrococcus horikoshii
Mol. Biosyst.
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74-81
2011
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1
8
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2
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8
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1
2
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4
2
1
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1
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1
1
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723263
Zhang
Lin, H.: Diphthamide biosynthe ...
Pyrococcus horikoshii
Nature
465
891-896
2010
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2
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725594
Webb
Diphthamide modification of eE ...
Mus musculus
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121
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2008
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1
1
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718109
Liu
Identification of the proteins ...
Saccharomyces cerevisiae, Mus musculus
Mol. Cell. Biol.
24
9487-9497
2004
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725093
Mattheakis
Diphthamide synthesis in Sacch ...
Saccharomyces cerevisiae, Saccharomyces cerevisiae FY251
Gene
132
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1993
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