Cloned (Comment) | Organism |
---|---|
- |
Mus musculus |
Protein Variants | Comment | Organism |
---|---|---|
D242N/D244N | glucuronyltransferase activity is comparable to that in wild type, whereas xylosyltransferase activity is undetectable | Mus musculus |
D563N/D565N | glucuronyltransferase activity is comparable to that in wild type, whereas xylosyltransferase activity is undetectable | Mus musculus |
additional information | expression of a secreted form that lack the transmembrane domain | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Mus musculus | 16020 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | Q5XPT3 | isoform LARGE2 | - |
Mus musculus | Q9Z1M7 | isoform LARGE1 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | enzyme acts as a bifunctional glycosyltransferase, with both xylosyltransferase and glucuronyltransferase activities, producing repeating units of [3-alpha-D-xylosyl-(1->3)-beta-D-glucuronyl-1-] | Mus musculus | ? | - |
- |
|
additional information | enzyme is specific for transfer of D-xylose and D-glucuronate | Mus musculus | ? | - |
- |
|
UDP-alpha-D-glucuronate + 4-nitrophenyl alpha-D-xyloside | glucuronosyltransferase activity of the bifunctional enzyme | Mus musculus | UDP + 4-nitrophenyl beta-D-glucuronyl-(1->3)-alpha-D-xyloside | - |
? | |
UDP-alpha-D-xylose + 4-methylumbelliferyl beta-D-glucuronate | xylosyltransferase activity of the bifunctional enzyme | Mus musculus | UDP + 4-methylumbelliferyl alpha-D-xylosyl-(1->3)-beta-D-glucuronate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
LARGE1 | - |
Mus musculus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
5 | - |
xylosyltransferase activity, recombinant protein lacking the transmembrane domain | Mus musculus |
5.5 | - |
glucuronyltransferase activity, recombinant protein lacking the transmembrane domain | Mus musculus |
5.5 | 8 | glucuronyltransferase activity, recombinant protein lacking the transmembrane domain | Mus musculus |
5.5 | 9 | xylosyltransferase activity, recombinant protein lacking the transmembrane domain | Mus musculus |