Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | AftC is active only when reconstituted in a proteoliposome | Mycobacterium tuberculosis |
Cloned (Comment) | Organism |
---|---|
expressed in Mycobacterium smegmatis mc2155/pJAM/Rv2673 cells | Mycobacterium tuberculosis |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Mycobacterium tuberculosis | 16020 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
38000 | - |
x * 38000, SDS-PAGE | Mycobacterium tuberculosis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycobacterium tuberculosis | - |
- |
- |
Mycobacterium tuberculosis H37Rv | - |
- |
- |
Purification (Comment) | Organism |
---|---|
metal affinity column column chromatography | Mycobacterium tuberculosis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(2Z,6Z)-farnesylphospho-alpha-D-arabinofuranoside + octyl (alpha-D-Araf)2-(1->3,5)-alpha-D-Araf-(1->5)-alpha-D-Araf-(1->5)-alpha-D-Araf | - |
Mycobacterium tuberculosis | ? | - |
? | |
(2Z,6Z)-farnesylphospho-alpha-D-arabinofuranoside + octyl (alpha-D-Araf)2-(1->3,5)-alpha-D-Araf-(1->5)-alpha-D-Araf-(1->5)-alpha-D-Araf | - |
Mycobacterium tuberculosis H37Rv | ? | - |
? | |
(2Z,6Z)-farnesylphospho-alpha-D-arabinofuranoside + octyl alpha-D-Araf-(1->5)-alpha-D-Araf-(1->5)-alpha-D-Araf-(1->5)-alpha-D-Araf-(1->5)-alpha-D-Araf | - |
Mycobacterium tuberculosis | ? | - |
? | |
(2Z,6Z)-farnesylphospho-alpha-D-arabinofuranoside + octyl alpha-D-Araf-(1->5)-alpha-D-Araf-(1->5)-alpha-D-Araf-(1->5)-alpha-D-Araf-(1->5)-alpha-D-Araf | - |
Mycobacterium tuberculosis H37Rv | ? | - |
? | |
decaprenylphospho-alpha-D-arabinofuranoside + octyl alpha-D-Araf-(1->5)-alpha-D-Araf-(1->5)-alpha-D-Araf-(1->5)-alpha-D-Araf-(1->5)-alpha-D-Araf | - |
Mycobacterium tuberculosis | ? | - |
? | |
decaprenylphospho-alpha-D-arabinofuranoside + octyl alpha-D-Araf-(1->5)-alpha-D-Araf-(1->5)-alpha-D-Araf-(1->5)-alpha-D-Araf-(1->5)-alpha-D-Araf | - |
Mycobacterium tuberculosis H37Rv | ? | - |
? | |
ditrans,tetracis-heptaprenylphospho-alpha-D-arabinofuranoside + octyl alpha-D-Araf-(1->5)-alpha-D-Araf-(1->5)-alpha-D-Araf-(1->5)-alpha-D-Araf-(1->5)-alpha-D-Araf | - |
Mycobacterium tuberculosis | ? | - |
? | |
additional information | no activity with octyl alpha-D-Araf-(1->5)-alpha-D-Araf and dipalmitoyl phosphatidylcholine | Mycobacterium tuberculosis | ? | - |
? | |
additional information | the enzyme introduces alpha-(1->3) branch points in the internal arabinan domain in both arabinogalactan and lipoarabinomannan synthesis. The enzyme can only transfer D-arabinofuranose when a minimum of three arabinofuranosyl residues are present in a linear structure in order to introduce an alpha-D-Araf-(1->3) branch point | Mycobacterium tuberculosis | ? | - |
? | |
additional information | no activity with octyl alpha-D-Araf-(1->5)-alpha-D-Araf and dipalmitoyl phosphatidylcholine | Mycobacterium tuberculosis H37Rv | ? | - |
? | |
additional information | the enzyme introduces alpha-(1->3) branch points in the internal arabinan domain in both arabinogalactan and lipoarabinomannan synthesis. The enzyme can only transfer D-arabinofuranose when a minimum of three arabinofuranosyl residues are present in a linear structure in order to introduce an alpha-D-Araf-(1->3) branch point | Mycobacterium tuberculosis H37Rv | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 38000, SDS-PAGE | Mycobacterium tuberculosis |
Synonyms | Comment | Organism |
---|---|---|
1,3-alpha-arabinosyltransferase | - |
Mycobacterium tuberculosis |
AftC | - |
Mycobacterium tuberculosis |
Rv2673 | - |
Mycobacterium tuberculosis |
General Information | Comment | Organism |
---|---|---|
metabolism | the enzyme is involved in the synthesis of the internal alpha-(1->3)-branching of the arabinan domain of arabinogalactan | Mycobacterium tuberculosis |