Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.4.2.43 extracted from

  • Sato, T.; Shiraishi, T.; Hiyama, Y.; Honda, H.; Shinagawa, M.; Usui, M.; Kuronuma, K.; Masumori, N.; Takahashi, S.; Tamura, Y.; Yokota, S.I.
    Contribution of novel amino acid alterations in PmrA or PmrB to colistin resistance in mcr-negative Escherichia coli clinical isolates, including major multidrug-resistant lineages O25b H4-ST131-H30Rx and Non-x (2018), Antimicrob. Agents Chemother., 62, e00864-18 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.4.2.43

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4-amino-4-deoxy-alpha-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate + alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A Escherichia coli
-
 alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-[4-P-L-Ara4N]-lipid A + ditrans,octacis-undecaprenyl phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
 isolates SRE34, SRE44, SME296, and SME222
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-amino-4-deoxy-alpha-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate + alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A
-
 Escherichia coli alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-[4-P-L-Ara4N]-lipid A + ditrans,octacis-undecaprenyl phosphate
-
 ?

Synonyms

Synonyms Comment Organism
arnT
-
 Escherichia coli
undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase
-
 Escherichia coli

Expression

Organism Comment Expression
Escherichia coli colistin-resistant Escherichia coli isolates display significantly increased mRNA levels for the enzyme gene up