Crystallization (Comment) | Organism |
---|---|
mutant enzymes N138A, P180A, R193L, R193A, R194A, and G107P, hanging drop vapor diffusion method, using | Mycobacterium tuberculosis |
Protein Variants | Comment | Organism |
---|---|---|
R193L | inactive | Mycobacterium tuberculosis |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
anthranilate | substrate inhibition | Mycobacterium tuberculosis |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | dependent on | Mycobacterium tuberculosis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-(5-phospho-D-ribosyl)-anthranilate + diphosphate | Mycobacterium tuberculosis | - |
anthranilate + 5-phospho-alpha-D-ribose 1-diphosphate | - |
? | |
N-(5-phospho-D-ribosyl)-anthranilate + diphosphate | Mycobacterium tuberculosis H37Rv | - |
anthranilate + 5-phospho-alpha-D-ribose 1-diphosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycobacterium tuberculosis | P9WFX5 | - |
- |
Mycobacterium tuberculosis H37Rv | P9WFX5 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-(5-phospho-D-ribosyl)-anthranilate + diphosphate | - |
Mycobacterium tuberculosis | anthranilate + 5-phospho-alpha-D-ribose 1-diphosphate | - |
? | |
N-(5-phospho-D-ribosyl)-anthranilate + diphosphate | - |
Mycobacterium tuberculosis H37Rv | anthranilate + 5-phospho-alpha-D-ribose 1-diphosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
AnPRT | - |
Mycobacterium tuberculosis |