Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-alpha-D-glucose + 2-hydroxynaringenin | Fagopyrum esculentum | - |
UDP + ? | - |
? | |
UDP-alpha-D-glucose + a 2'-hydroxy-beta-oxodihydrochalcone | Fagopyrum esculentum | - |
UDP + a 3'-(beta-D-glucopyranosyl)-2'-hydroxy-beta-oxodihydrochalcone | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Fagopyrum esculentum | A0A0A1H7N4 | - |
- |
Fagopyrum esculentum | A0A0A1HA03 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cotyledon | immature, 3-5 days after sawing | Fagopyrum esculentum | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-alpha-D-glucose + 2-hydroxynaringenin | - |
Fagopyrum esculentum | UDP + ? | - |
? | |
UDP-alpha-D-glucose + a 2'-hydroxy-beta-oxodihydrochalcone | - |
Fagopyrum esculentum | UDP + a 3'-(beta-D-glucopyranosyl)-2'-hydroxy-beta-oxodihydrochalcone | - |
? |
Synonyms | Comment | Organism |
---|---|---|
UGT708C1 | - |
Fagopyrum esculentum |
UGT708C2 | - |
Fagopyrum esculentum |
General Information | Comment | Organism |
---|---|---|
metabolism | the enzyme is involved in the proposed biosynthetic pathway of C-glucosylflavones in buckwheat, overview. It starts with the hydroxylation of the 2-position of flavanone, which is the intermedixadate product of flavonol biosynthesis. The produced 2-hydroxyflavanone is in equilibrium with one of its open-circular forms (2',4',6'-trihydroxyacetophenone-like structure, dibenzoylxadmethane form), which is C-glucosylated by CGT. The formed C-glucoside is also in equilibrium with its two closed-circular forms, that is, 2-hydroxyflavanone 6-C-glucoside and 8-C-glucoside, because the sugar moiety of the open-circular form of C-glucoside can be rotated. They are then enzymatically dehydrated to produce two C-glucosylflavones | Fagopyrum esculentum |
physiological function | FeCGT enxadzymes (UGT708C1 and UGT708C2) show C-glucosylation activity toward 2-hydroxyflavanones and related compounds having a 2',4',6'-trihydroxyacetophenone-like structure but not toward flavones or flavonols, indicating that the open-circular form of 2-hydroxyflavanones is their substrate | Fagopyrum esculentum |