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Literature summary for 2.4.1.212 extracted from

  • Nykopp, T.; Rilla, K.; Sironen, R.; Tammi, M.; Tammi, R.; Hämäläinen, K.; Heikkinen, A.; Komulainen, M.; Kosma, V.; Anttila, M.
    Expression of hyaluronan synthases (HAS1-3) and hyaluronidases (HYAL1-2) in serous ovarian carcinomas: Inverse correlation between HYAL1 and hyaluronan content (2009), BMC Cancer, 9, 143.
    View publication on PubMedView publication on EuropePMC
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Application

Application Comment Organism
medicine in serous epithelial ovarian tumors, expression of HAS1 is low or absent. The levels of HAS2 and HAS3 mRNA are not consistently increased in the carcinomas, and are not significantly correlated with HAS protein or hyaluronan accumulation in individual samples Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens O00219 isoform HAS3
-
Homo sapiens Q92819 isoform HAS2
-

Source Tissue

Source Tissue Comment Organism Textmining
ovarian serous carcinoma cell serous epithelial ovarian tumor Homo sapiens
-
ovary serous epithelial ovarian tumor Homo sapiens
-
ovary epithelium cell line serous epithelial ovarian tumor Homo sapiens
-

Synonyms

Synonyms Comment Organism
Has3
-
 Homo sapiens
hyaluronan synthase 2
-
 Homo sapiens