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Literature summary for 2.3.1.B41 extracted from

  • Wu, M.; Dickinson, S.I.; Wang, X.; Zhang, J.
    Expression and function of SIRT6 in muscle invasive urothelial carcinoma of the bladder (2014), Int. J. Clin. Exp. Pathol., 7, 6504-6513.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Homo sapiens Q8N6T7
-
-

Source Tissue

Source Tissue Comment Organism Textmining
5637 cell
-
Homo sapiens
-
bladder transitional cell carcinoma cell line muscle invasive urothelial carcinoma of the bladder. Decline of SIRT6 expression when bladder cancer progresses from stage T2 to stage T4 Homo sapiens
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UM-UC-3 cell
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Homo sapiens
-

Synonyms

Synonyms Comment Organism
SIRT6
-
Homo sapiens

Expression

Organism Comment Expression
Homo sapiens decline of SIRT6 expression when bladder cancer progresses from stage T2 to stage T4 down

General Information

General Information Comment Organism
malfunction knock-down of SIRT6 does not sensitize bladder cancer cell lines to DNA damaging drugs Homo sapiens
metabolism SIRT6 suppresses glycolysis in bladder cancer cells Homo sapiens