Crystallization (Comment) | Organism |
---|---|
in complex with both myristoyl-CoA and inhibitor N-(10-aminodecanoyl)-L-seryl-N-(2-cyclohexylethyl)-L-lysinamide. The inhibitor sits in the peptide-binding pocket, and mimics the key recognition elements involved in binding the parent peptide | Plasmodium vivax |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
N-(10-aminodecanoyl)-L-seryl-N-(2-cyclohexylethyl)-L-lysinamide | peptidomimetic inhibitor | Homo sapiens | |
N-(10-aminodecanoyl)-L-seryl-N-(2-cyclohexylethyl)-L-lysinamide | peptidomimetic inhibitor | Leishmania donovani | |
N-(10-aminodecanoyl)-L-seryl-N-(2-cyclohexylethyl)-L-lysinamide | peptidomimetic inhibitor | Plasmodium falciparum | |
N-(10-aminodecanoyl)-L-seryl-N-(2-cyclohexylethyl)-L-lysinamide | peptidomimetic inhibitor | Plasmodium vivax |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P30419 | - |
- |
Leishmania donovani | D0AB09 | - |
- |
Plasmodium falciparum | - |
- |
- |
Plasmodium vivax | A5K1A2 | - |
- |
Plasmodium vivax Salvador I | A5K1A2 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
PVX_085815 | - |
Plasmodium vivax |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.000024 | - |
pH not specified in the publication, temperature not specified in the publication | Leishmania donovani | N-(10-aminodecanoyl)-L-seryl-N-(2-cyclohexylethyl)-L-lysinamide | |
0.00006 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | N-(10-aminodecanoyl)-L-seryl-N-(2-cyclohexylethyl)-L-lysinamide | |
0.00068 | - |
pH not specified in the publication, temperature not specified in the publication | Plasmodium vivax | N-(10-aminodecanoyl)-L-seryl-N-(2-cyclohexylethyl)-L-lysinamide | |
0.0243 | - |
pH not specified in the publication, temperature not specified in the publication | Plasmodium falciparum | N-(10-aminodecanoyl)-L-seryl-N-(2-cyclohexylethyl)-L-lysinamide |