Activating Compound | Comment | Organism | Structure |
---|---|---|---|
EDTA | slight activation | Saccharomyces cerevisiae |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,10-phenanthroline | 0.1 mM, 30% inhibition | Saccharomyces cerevisiae | |
diethyldicarbonate | - |
Saccharomyces cerevisiae | |
p-hydroxymercuribenzoate | - |
Saccharomyces cerevisiae |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | - |
Saccharomyces cerevisiae | |
0.016 | - |
Gly-Asn-Ala-Ala-Ala-Ala-Arg-Arg | - |
Saccharomyces cerevisiae | |
0.016 | - |
Gly-(diaminobutyrate-gamma-NH2-4-azido-3-iodosalicylamide)-L-Ala-L-Ala-L-Ser-S-Ala-L-Arg-L-Arg | - |
Saccharomyces cerevisiae | |
0.04 | - |
Gly-Ser-Ser-Lys-Ser-Lys-Pro-Lys | - |
Saccharomyces cerevisiae | |
0.06 | - |
Gly-Asn-Ala-Ala-Ala-Ala-Arg-Arg | - |
Saccharomyces cerevisiae | |
0.06 | - |
Gly-Asn-Phe-Ala-Ala-Ala-Arg-Arg | - |
Saccharomyces cerevisiae | |
0.3 | - |
Gly-Asn-Ala-Pro-Ala-Ala-Arg-Arg | - |
Saccharomyces cerevisiae | |
0.3 | - |
Gly-Ala-Arg-Ala-Ala-Ala-Ala-Arg-Arg | - |
Saccharomyces cerevisiae | |
1.3 | - |
Gly-Asn-Ala-Ala-Ala-Ala | - |
Saccharomyces cerevisiae |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
additional information | no requirement for divalent cations | Saccharomyces cerevisiae |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
55000 | - |
gel filtration | Saccharomyces cerevisiae |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Saccharomyces cerevisiae |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
tetradecanoyl-CoA + an N-terminal-glycyl-[protein] = CoA + an N-terminal-N-tetradecanoylglycyl-[protein] | requires alanine at position 5 of substrate peptides | Saccharomyces cerevisiae |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
myristoyl-CoA + Gly-Ala-Arg-Ala-Ala-Ala-Ala-Arg-Arg | - |
Saccharomyces cerevisiae | N-myristoyl-Gly-Ala-Arg-Ala-Ala-Ala-Ala-Arg-Arg + CoA | - |
? | |
myristoyl-CoA + Gly-Asn-Ala-Ala-Ala-Ala | - |
Saccharomyces cerevisiae | N-myristoyl-Gly-Asn-Ala-Ala-Ala-Ala + CoA | - |
? | |
myristoyl-CoA + Gly-Asn-Ala-Ala-Ala-Ala-Arg-Arg | - |
Saccharomyces cerevisiae | N-myristoyl-Gly-Asn-Ala-Ala-Ala-Ala-Arg-Arg + CoA | - |
? | |
myristoyl-CoA + Gly-Asn-Ala-Pro-Ala-Ala-Arg-Arg | - |
Saccharomyces cerevisiae | N-myristoyl-Gly-Asn-Ala-Pro-Ala-Ala-Arg-Arg + CoA | - |
? | |
myristoyl-CoA + Gly-Asn-Phe-Ala-Ala-Ala-Arg-Arg | - |
Saccharomyces cerevisiae | N-myristoyl-Gly-Asn-Phe-Ala-Ala-Ala-Arg-Arg + CoA | - |
? | |
myristoyl-CoA + Gly-Ser-Ser-Lys-Ser-Lys-Pro-Lys | - |
Saccharomyces cerevisiae | N-myristoyl-Gly-Ser-Ser-Lys-Ser-Lys-Pro-Lys + CoA | - |
? | |
myristoyl-CoA + glycylpeptide | substrate specificity | Saccharomyces cerevisiae | N-myristoylglycylpeptide + CoA | - |
? | |
myristoyl-CoA + glycylpeptide | myristoyl-peptides can compete with myristoyl-CoA for the binding site | Saccharomyces cerevisiae | N-myristoylglycylpeptide + CoA | - |
? | |
myristoyl-CoA + glycylpeptide | overview peptides and proteins | Saccharomyces cerevisiae | N-myristoylglycylpeptide + CoA | - |
? | |
myristoyl-CoA + glycylpeptide | specific for Gly at N-terminus | Saccharomyces cerevisiae | N-myristoylglycylpeptide + CoA | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 55000, SDS-PAGE | Saccharomyces cerevisiae |
Synonyms | Comment | Organism |
---|---|---|
NMT | - |
Saccharomyces cerevisiae |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | 8 | - |
Saccharomyces cerevisiae |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
7 | 9 | about half-maximal activity above pH 9.0 and below pH 7.0, inactive at pH 6.0 | Saccharomyces cerevisiae |