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Literature summary for 2.3.1.7 extracted from

  • Berg, S.M.; Beck-Nielsen, H.; Faergeman, N.J.; Gaster, M.
    Carnitine acetyltransferase A new player in skeletal muscle insulin resistance? (2017), Biochem. Biophys. Rep., 9, 47-50 .
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine CRAT function is not the major contributor to primary insulin resistance in cultured myotubes obtained from obese type 2 diabetes mellitus patients. mRNA levels and protein abundance of CRAT are similar between from obese persons with or without type 2 diabetes mellitus and lean controls. Of 14 different acylcarnitine species measured, the levels of palmitoylcarnitine and octadecanoylcarnitine are slightly reduced in myotubes derived from type 2 diabetes mellitus patients compared to glucose-tolerant obese and lean controls Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P43155
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