Application | Comment | Organism |
---|---|---|
medicine | exposure of lung epithelial cells to pathophysiologically relevant amounts of oxidants such as H2O2 or peroxyntrite, impairs the Nat1-dependent cellular biotransformation of aromatic amines | Homo sapiens |
medicine | exposure of lung epithelial cells to pathophysiologically relevant amounts of oxidants such as H2O2 or peroxyntrite, impairs the Nat2-dependent cellular biotransformation of aromatic amines | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
alveolar cell | type II alveolar cell, presence of isoform Nat1. Exposure of cells to pathophysiologically relevant amounts of oxidants such as H2O2 or peroxyntrite, impairs the cellular biotransformation of aromatic amines | Homo sapiens | - |
alveolar cell | type II alveolar cell, presence of isoform Nat2. Exposure of cells to pathophysiologically relevant amounts of oxidants such as H2O2 or peroxyntrite, impairs the cellular biotransformation of aromatic amines | Mus musculus | - |
bronchial epithelial cell | presence of isoform Nat1. Exposure of cells to pathophysiologically relevant amounts of oxidants such as H2O2 or peroxyntrite, impairs the cellular biotransformation of aromatic amines | Homo sapiens | - |
bronchial epithelial cell | presence of isoform Nat2. Exposure of cells to pathophysiologically relevant amounts of oxidants such as H2O2 or peroxyntrite, impairs the cellular biotransformation of aromatic amines | Mus musculus | - |
Clara cell | presence of isoform Nat1. Exposure of cells to pathophysiologically relevant amounts of oxidants such as H2O2 or peroxyntrite, impairs the cellular biotransformation of aromatic amines | Homo sapiens | - |
epithelial cell | presence of isoform Nat1. Exposure of cells to pathophysiologically relevant amounts of oxidants such as H2O2 or peroxyntrite, impairs the cellular biotransformation of aromatic amines | Homo sapiens | - |
epithelial cell | presence of isoform Nat2. Exposure of cells to pathophysiologically relevant amounts of oxidants such as H2O2 or peroxyntrite, impairs the cellular biotransformation of aromatic amines | Mus musculus | - |
lung | presence of isoform Nat1 | Homo sapiens | - |
lung | presence of isoform Nat2 | Mus musculus | - |