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Literature summary for 2.3.1.5 extracted from

  • Geylan-Su, Y.S.; Isgoer, B.; Coban, T.; Kapucuoglu, N.; Aydintug, S.; Iscan, M.; Iscan, M.; Gueray, T.
    Comparison of NAT1, NAT2 and GSTT2-2 activities in normal and neoplastic human breast tissues (2006), Neoplasma, 53, 73-78.
    View publication on PubMed
Search for more literature for 2.3.1.5

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens isozyme NAT1 is not increased in breast tumors compared to healthy tissue, the grade of malignancy is positively related with NAT1 ?
-
 ?
additional information Homo sapiens isozyme NAT2 is increased in breast tumors compared to healthy tissue, the grade of malignancy is negatively associated with NAT2 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens P11245 isozyme NAT2; isozyme NAT2
-
Homo sapiens P18440 isozyme NAT1; isozyme NAT1
-

Source Tissue

Source Tissue Comment Organism Textmining
breast healthy and neoplastic tissue Homo sapiens
-
breast cancer cell patients with ductal carcinoma Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 isozyme activities in healthy and tumor breast tissue, overview Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information isozyme NAT1 is not increased in breast tumors compared to healthy tissue, the grade of malignancy is positively related with NAT1 Homo sapiens ?
-
 ?
additional information isozyme NAT2 is increased in breast tumors compared to healthy tissue, the grade of malignancy is negatively associated with NAT2 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
NAT
-
 Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
 assay at Homo sapiens