Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
NAD+ + [nuclear receptor LXR]-N6-acetyl-L-lysine | Homo sapiens | SIRT1 positively regulates liver X receptors (LXRs) by deacetylation at lysine. Deacetylation of liver X receptors (LXRs) by SIRT1 may be a mechanism that affects atherosclerosis and other agingassociated diseases | nicotinamide + [nuclear receptor LXR]-L-lysine + 2'-O-acetyl-ADP ribose | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q96EB6 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
NAD+ + [nuclear receptor LXRalpha]-N6-acetyl-L-lysine432 | - |
Homo sapiens | nicotinamide + [nuclear receptor LXRalpha]-L-lysine432 + 2'-O-acetyl-ADP ribose | - |
? | |
NAD+ + [nuclear receptor LXRbeta]-N6-acetyl-L-lysine433 | - |
Homo sapiens | nicotinamide + [nuclear receptor LXRbeta]-L-lysine433 + 2'-O-acetyl-ADP ribose | - |
? | |
NAD+ + [nuclear receptor LXR]-N6-acetyl-L-lysine | SIRT1 positively regulates liver X receptors (LXRs) by deacetylation at lysine. Deacetylation of liver X receptors (LXRs) by SIRT1 may be a mechanism that affects atherosclerosis and other agingassociated diseases | Homo sapiens | nicotinamide + [nuclear receptor LXR]-L-lysine + 2'-O-acetyl-ADP ribose | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SIRT1 | - |
Homo sapiens |