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Literature summary for 2.3.1.225 extracted from

  • Ko, P.J.; Woodrow, C.; Dubreuil, M.M.; Martin, B.R.; Skouta, R.; Bassik, M.C.; Dixon, S.J.
    A ZDHHC5-GOLGA7 protein acyltransferase complex promotes nonapoptotic cell death (2019), Cell Chem. Biol., 26, 1716-1724 .
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9C0B5
-
-

Synonyms

Synonyms Comment Organism
ZDHHC5
-
Homo sapiens

General Information

General Information Comment Organism
physiological function CIL56 is a synthetic oxime that can trigger a form of nonapoptotic cell death that is distinct from apoptosis, necroptosis, ferroptosis, and classic necrosis. This unconventional form of cell death is promoted by a plasma membrane protein acyltransferase complex comprising ZDHHC5 and GOLGA7 Homo sapiens