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Literature summary for 2.3.1.21 extracted from

  • Lee, J.; Hyon, J.; Min, J.; Huh, Y.; Kim, H.; Lee, H.; Yun, S.; Choi, C.; Jeong Ha, S.; Park, J.; Chung, Y.; Jeong, H.; Ha, S.; Jung, S.; Kim, Y.; Han, E.
    Mitochondrial carnitine palmitoyltransferase 2 is involved in Nepsilon-(carboxymethyl)-lysine-mediated diabetic nephropathy (2020), Pharmacol. Res., 152, 104600 .
    View publication on PubMed
Search for more literature for 2.3.1.21

Organism

Organism UniProt Comment Textmining
Homo sapiens P23786
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-

Source Tissue

Source Tissue Comment Organism Textmining
HK-2 cell
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 Homo sapiens
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Synonyms

Synonyms Comment Organism
CPT2
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function treatment with Nepsilon-(carboxymethyl)-lysine-bovine serum albumin and CPT2 knockdown induce fibrosis-related gene expression and damage mitochondrial membrane potential, leading to renal fibrosis and diabetic nephropathy. CPT2 overexpression reverses Nepsilon-(carboxymethyl)-lysine-induced fibrosis-related gene expression Homo sapiens