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Literature summary for 2.3.1.21 extracted from

  • Ramsay, R.R.; Mancinelli, G.; Arduini, A.
    Carnitine palmitoyltransferase in human erythrocyte membrane. Properties and malonyl-CoA sensitivity (1991), Biochem. J., 275, 685-688.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.1.21

General Stability

General Stability Organism
Triton X-100: erythrocyte plasma membrane enzyme is stable, enzyme from microsomes and mitochondrial outer membrane not Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
2-bromopalmitoyl-CoA with addition of carnitine Homo sapiens
malonyl-CoA
-
 Homo sapiens
Triton X-100 erythrocyte enzyme is not affected Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Homo sapiens 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acyl-CoA + L-carnitine Homo sapiens
-
 CoA + L-acylcarnitine
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acyl-CoA + L-carnitine
-
 Homo sapiens CoA + L-acylcarnitine
-
 ?
acyl-CoA + L-carnitine substrate specificity Homo sapiens CoA + L-acylcarnitine
-
 ?
arachidoyl-CoA + L-carnitine
-
 Homo sapiens CoA + L-arachidoylcarnitine
-
 ?
decanoyl-CoA + L-carnitine best substrate Homo sapiens CoA + L-decanoylcarnitine
-
 ?
erucoyl-CoA + L-carnitine
-
 Homo sapiens CoA + L-erucoylcarnitine
-
 ?
linoleoyl-CoA + L-carnitine
-
 Homo sapiens CoA + L-linoleoylcarnitine
-
 ?
palmitoyl-CoA + L-carnitine
-
 Homo sapiens CoA + L-palmitoylcarnitine
-
 ?
stearoyl-CoA + L-carnitine
-
 Homo sapiens CoA + L-stearoylcarnitine
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
 assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
 assay at Homo sapiens