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Literature summary for 2.3.1.147 extracted from

  • Winkler, J.D.; Sung, C.M.; Marshall, L.A.; Chilton, F.H.
    Inhibitors of arachidonate metabolism and effects on PAF production (1996), Adv. Exp. Med. Biol., 416, 11-45.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
1-[2-[3-(4-Chloro-3-trifluoromethylphenyl)ureido]-4-trifluoromethyl phenoxy]-4,5-dichlorobenzene sulfonic acid i.e. SK&F 45905 Homo sapiens
Diethyl 7-(3,4,5-triphenyl-2-oxo-2,3-dihydro-imidazol-1-yl)heptane-phosphonate i.e. SK&F 98625 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens EC 2.3.1.147 and 14000 MW phospholipase A act in a cooperative fashion in the production of platelet-activating factor in inflammatory cells ?
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?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
monocyte
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information selectively transfers arachidonate and other long-chain unsaturated fatty acyl groups. Strong preference for phosphocholine-containing glycerophospholipids and phosphoethanolamine-containing glycerophospholipids Homo sapiens ?
-
?
additional information EC 2.3.1.147 and 14000 MW phospholipase A act in a cooperative fashion in the production of platelet-activating factor in inflammatory cells Homo sapiens ?
-
?