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Literature summary for 2.1.1.67 extracted from

  • Citterio-Quentin, A.; El Mahmoudi, A.; Perret, T.; Conway, A.; Ryan, A.; Beringer, A.; Lachaux, A.; Boulieu, R.
    Red Blood cell IMPDH activity in adults and children with or without azathioprine Relationship between thiopurine metabolites, ITPA and TPMT activities (2019), Basic Clin. Pharmacol. Toxicol., 124, 600-606 .
    View publication on PubMed
Search for more literature for 2.1.1.67

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
erythrocyte
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + 6-mercaptopurine
-
 Homo sapiens S-adenosyl-L-homocysteine + 6-methylmercaptopurine
-
 ?
S-adenosyl-L-methionine + 6-thioinosine diphosphate
-
 Homo sapiens S-adenosyl-L-homocysteine + 6-methylthioinosine diphosphate
-
 ?
S-adenosyl-L-methionine + 6-thioinosine monophosphate
-
 Homo sapiens S-adenosyl-L-homocysteine + 6-methyl thioinosine monophosphate
-
 ?
S-adenosyl-L-methionine + 6-thioinosine triphosphate
-
 Homo sapiens S-adenosyl-L-homocysteine + 6-methylthioinosine triphosphate
-
 ?

Synonyms

Synonyms Comment Organism
thiopurine methyltransferase
-
 Homo sapiens
TPMT
-
 Homo sapiens