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Literature summary for 2.1.1.67 extracted from
- Thiopurine methyltransferase activity is related to the risk of relapse of childhood acute lymphoblastic leukemia: results from the NOPHO ALL-92 study (2009), Leukemia, 23, 557-564.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| S-adenosyl-L-methionine + 6-thiopurine | Homo sapiens | - |
S-adenosyl-L-homocysteine + 6-methylthiopurine | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| erythrocyte | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| S-adenosyl-L-methionine + 6-thiopurine | - |
Homo sapiens | S-adenosyl-L-homocysteine + 6-methylthiopurine | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| thiopurine methyltransferase | - |
Homo sapiens |
| TPMT | - |
Homo sapiens |
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