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Literature summary for 2.1.1.67 extracted from

  • Loo, G.; Smith, J.T.
    Glutathione: an endogenous substrate for thiopurine methyltransferase? (1985), Biochem. Biophys. Res. Commun., 126, 1201-1207.
    View publication on PubMed
Search for more literature for 2.1.1.67

Inhibitors

Inhibitors Comment Organism Structure
glutathione
-
 Rattus norvegicus
S-Methylglutathione
-
 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Rattus norvegicus 5829
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + a thiopurine Rattus norvegicus
-
 S-adenosyl-L-homocysteine + a thiopurine S-methylether
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 rat, Sprague-Dawley
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information glutathione is no substrate Rattus norvegicus ?
-
 ?
S-adenosyl-L-methionine + 6-thiopurine
-
 Rattus norvegicus S-adenosyl-L-homocysteine + 6-methylthiopurine
-
 ?
S-adenosyl-L-methionine + a thiopurine
-
 Rattus norvegicus S-adenosyl-L-homocysteine + a thiopurine S-methylether
-
 ?