Inhibitors | Comment | Organism | Structure |
---|---|---|---|
aurintricarboxylic acid | strong inhibition at 0.025 mM | Dengue virus | |
aurintricarboxylic acid | strong inhibition at 0.025 mM | Wesselsbron virus | |
additional information | nilutamide and PPDNS do not display efficient inhibition at 0.025 and 0.125 mM | Dengue virus | |
additional information | nilutamide and PPDNS do not display efficient inhibition at 0.025 and 0.125 mM | Wesselsbron virus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Dengue virus | - |
- |
- |
Wesselsbron virus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Dengue virus |
- |
Wesselsbron virus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + G(5')pppR-RNA | - |
Dengue virus | S-adenosyl-L-homocysteine + m7G(5')pppR-RNA | - |
? | |
S-adenosyl-L-methionine + G(5')pppR-RNA | - |
Wesselsbron virus | S-adenosyl-L-homocysteine + m7G(5')pppR-RNA | - |
? |
Synonyms | Comment | Organism |
---|---|---|
guanine-N7 methyltransferase | - |
Dengue virus |
guanine-N7 methyltransferase | - |
Wesselsbron virus |
N7 methyltransferase | - |
Dengue virus |
N7 methyltransferase | - |
Wesselsbron virus |
N7 MTase | - |
Dengue virus |
N7 MTase | - |
Wesselsbron virus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0023 | - |
in 50 mM Tris, pH 7.0, 50 mM NaCl, 2 mM dithiothreitol, at 22°C | Dengue virus | aurintricarboxylic acid | |
0.0042 | - |
in 50 mM Tris, pH 7.0, 50 mM NaCl, 2 mM dithiothreitol, at 22°C | Wesselsbron virus | aurintricarboxylic acid |