Application | Comment | Organism |
---|---|---|
analysis | synthesis of acyclic nucleosides containing a 5-fluorouracil nucleobase, FC-ac1, and FC-ac2 to study the reaction mechanism. The oligodeoxynucleotides containing ODN-FC-ac1 and ODN-FC-ac2 show an increased flexiblilty. A negative correlation is observed between the flexibility and ODN-DNMT complex formation. A weaker nucleobase stacking effect due to the increase in flexibility at the acyclic modification site may provide a higher flip out effect, while the local flexibility would influence the scanning and recognition steps | Haemophilus parahaemolyticus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Haemophilus parahaemolyticus | P05102 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine | - |
Haemophilus parahaemolyticus | a 5-methyl-2'-deoxycytidine in DNA + H+ + S-adenosyl-L-homocysteine | - |
? | |
additional information | the entire reaction mechanism of DNMT is divided into six steps, which are scanning, recognition, flipping, loop locking, methylation, and releasing. | Haemophilus parahaemolyticus | ? | - |
- |
Synonyms | Comment | Organism |
---|---|---|
hhaIM | - |
Haemophilus parahaemolyticus |
M.HhaI | - |
Haemophilus parahaemolyticus |