Application | Comment | Organism |
---|---|---|
analysis | development of a simple reliable label-free MALDI-TOF MS-based assay for the detection and quantification of peptide methylation, using SET7/9 as a model enzyme. The use of expensive internal standard often required in mass spectrometry quantitative analysis is not necessary in this assay | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
sinefungin | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q8WTS6 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ARTKQTARKSTGGKAPRK(biot)G + S-adenosyl-L-methionine | - |
Homo sapiens | ART-methyl-KQTARKSTGGKAPRK(biot)G + S-adenosyl-L-homocysteine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SET7/9 | - |
Homo sapiens |
SetD7 | - |
Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.02 | - |
pH 9.8, 37°C | Homo sapiens | sinefungin |