Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arabidopsis thaliana | - |
- |
- |
Danio rerio | - |
- |
- |
Drosophila melanogaster | - |
- |
- |
Mus musculus | - |
- |
- |
Saccharomyces cerevisiae | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
ALKBH5 | - |
Mus musculus |
FTO | - |
Mus musculus |
IME4 | - |
Drosophila melanogaster |
IME4 | - |
Saccharomyces cerevisiae |
METTL14 | - |
Mus musculus |
METTL14 | - |
Danio rerio |
METTL3 | - |
Mus musculus |
METTL3 | - |
Danio rerio |
MTA | - |
Arabidopsis thaliana |
YTHDF2 | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | depletion of isoforms METTL3 and METTL14 leads to apoptosis in cancer cells | Mus musculus |
physiological function | isoforms METTL3 and METTL4 are required for normal embryogenesis | Danio rerio |
physiological function | isoforms METTL3 and METTL4 regulate stem cell differentiation and reprogramming. Isoform METTL3 regulates circadian periods | Mus musculus |
physiological function | the enzyme is essential for viability and required for Notch signaling during oogenesis | Drosophila melanogaster |
physiological function | the enzyme is required for embryonic development , normal growth patterns, apical dominance, and plant development | Arabidopsis thaliana |
physiological function | the enzyme is required for meiosis and sporulation | Saccharomyces cerevisiae |